The mean pain-rating index (sum of 15 descriptors of SF-MPQ) was similar between cyclical and non-cyclical pain, and was 12. 16). • Justification of ordering additional data:Cyclic breast pain: Cyclic mastalgia affects women in their 20s, 30s, or 40s, while they are still menstruating. The breasts may be described as "lumpy" or "doughy". Both cyclical and non-cyclical mastalgia have an approximate response rate [1,17,18]. 7% had cyclic mastalgia and only 9. Tamoxifen at a dose of 10 mg / day for <6 months, continuous or limited to the luteal phase of the menstrual cycle, has shown an improvement in cyclic mastalgia in 70 to 90% and no clyclic mastalgia in 56% of cases 22. doi: 10. Mastodynia ICD-10-CM N64. Noncyclical breast pain is unrelated to the menstrual cycle and may occur in women (and men) who are not having menstrual periods. This article examines pain syndromes, including headache, back pain, osteoarthritis. psu. Cyclic mastalgia: a hormonal connection The most common type of breast pain is linked to the menstrual cycle, known as cyclic breast pain, and is nearly always based on hormonal fluctuations. That the general practitioners considered early diagnosis to be important was made evident from a number of the results, and the evidence showing that long-term survival may be greater when delays are shorter is encouraging. However, diffuse bilateral pain is very common in women. In Vaziri and et al. 5%) did not have PMS. No imaging correlates were discovered to explain the etiology of cyclical pain, supporting the American College of Radiology Appropriateness Criteria rating values. Cyclical mastalgia; Generalized tenderness of breast; Intractable breast pain; Localized tenderness of breast; Mastalgia of puberty; Mastodynia of bilateral. Introduction. In a prospective study by Plu-Bureau et al. Approximately 8-10% of premenopausal women experience moderate to severe. It is often located in the upper outer quadrant of the breastThe ICD code N644 is used to code Breast pain. Terasa lebih intens selama dua minggu menjelang awal periode menstruasi. A randomized, double‐blind, placebo‐controlled, multicenter clinical trial was conducted with 111 otherwise healthy euthyroid women with a history of breast pain and all doses were associated with an acceptable safety profile. 6%, and 22 women developed breast cancer. This type of mastalgia is experienced 2–3 days before the menstrual period as gentle nodules in the breast [ 2 , 9 , 10 ]. Diffuse bilateral pain may be caused by fibrocystic changes or, uncommonly, diffuse bilateral mastitis. Pain intensifies a couple of weeks before the start of periods, decreasing on the day when bleeding starts and subsides over the next few days. It is most common. The most affected ages are between 30–50 years . Breast pain (mastalgia) can be described as tenderness, throbbing, sharp, stabbing, burning pain or tightness in the breast tissue. a study in Ireland showed (3): 3,331 reported mastalgia as the only symptom Thirty-two premenopausal women reporting recent mastalgia completed breast pain and menstrual symptom scales daily for 3-6 months. 3% with cyclical nodularity, 6. The diagnosis codes found in the Tabular List and Alphabetic Index have been adopted under HIPAA for all healthcare settings. Mastalgia is common ailment that affects about 70% of women and has negative impact on their quality of life. Pain can be throbbing, pulsating, pinching, or radiating in character that is experienced with some degree of tenderness. In the cyclic mastalgia groups, the age range was 20 to 68 years (the mean age of group Ia was 41. Recommendations 1. The prevalence of cyclical mastalgia and its association with mammography replicate clinic-based findings. In previous studies which were conducted to evaluate the effect of flaxseed on cyclic mastalgia, a specific amount of flaxseed powder (25–30 g/d) was administered for patients [6, 19, 20]. This starter pack is exactly what every woman needs to bring her hormones back into balance!Cyclical mastalgia might last for more than 7 days in 11% of women . 4%) met criteria for clinically significant cyclical mastalgia, reporting an average of 10. The other type is noncyclic breast pain. RESULTS Seventy-nine percent reported having regularly experienced cyclical breast symptoms; 48% have asked a health care provider about their mastalgia. In the patients the severity of pain may adversely impact the routine life. 0 may differ. Results: The mean age of mastalgia (n=256) and control (n=200) patients were 35. 26,27. True mastalgia can be cyclic and exacerbate with menstrual cycles, or be non-cyclic and constant. Cyclic Mastalgia. The incidence of cyclical mastalgia in well women presenting for breast screening was 69 per cent. The pain is linked to menstrual periods. 54. Introduction. 2021. 1 The pain can be cyclical, beginning 5 to 10 days before menstruation and ending once the period starts, or it can be noncyclical, when the pain has no relation to the menstrual cycle. Or it may come from somewhere else, such as nearby muscles or joints, and may be felt in the breast. They stated that cyclical mastalgia increased the risk of breast cancer. 2 years). The data were also analyzed with the separation test by Aickin, which showed a trend toward a reduction of cyclical. Breast pain, also known as mastalgia, mastodynia, and mammalgia, is mild to intense pain in one or both breasts. Breast/chest pain is a common premenstrual symptom, typically occurring in the 5–10 days before the start of your period. Definition. 1 The episodes occur at variable intervals, with an average of 12 per year. The patient is requested to record her pain experience in terms of VLA score of “0” to “10. Certain hormonal factors underpin the function, evaluation, and treatment of this disease. Cyclical mastalgia. Treatment is based on patient symptoms and physical findings. Definition. Breast volume may increase by more than 100 mL during the luteal phase of the menstrual cycle due to the hormonal stimulation of breast. 18; vitamin E, p=0. Most breast cancers do not cause pain. Of 160 consecutive patients, 116 were diagnosed with NCBP and 44 controls. Assessment of risk for the development of breast cancer is important and is useful in patient reassurance or to design risk. Fibrocystic breasts have a lumpy, rope-like texture. Lebih rentan terjadi pada wanita usia 20-30an. There are 2 main types of mastalgia: Cyclical breast pain. Cyclical mastalgia ICD-10 code N64. 4 - other international versions of ICD-10 N64. Table 4. Article preview. Management of. This paper presents the first meta-analysis on the randomised trials published on the treatment of mastalgia. 5 ± 10. The efficacy of centchroman was found to be significant (p-value = 0. Benign breast disease in women is a very common finding and results in a diagnosis in approximately one million women annually in the United States (1). e. ICD-9-CM 611. Non-cyclical breast pain was subdivided into true non-cyclical mastalgia (35 patients) and musculoskeletal pain (37 patients), the latter including Tietze's syndrome and other causes of chest wall pain. In the new pain chart, the lady records pain severity in the form of visual linear analogue scale score on every day of menstrual cycle. The pain can range from minor discomfort to severely. 1A Although non-cyclical mastalgia has no such relationship, symptoms are often affected by hormonal. Thus, we carry out this study to determine the efficacy of evening primrose oil (EPO) for mastalgia treatment in women. To date, hormonal agents, despite their side effects, have been widely used for treatment of. Cyclic Mastalgia. Enrolled mastalgia patients were defined as those patients who were diagnosed with mastodynia (ICD-10-CM Code N64. Gumm R, Cunnick GH, Mokbel KCurr Med Res Opin 2004 May;20 (5):681-4. Geschickter CF. • mastalgia, mastodynia, or breast tenderness is a common problem experienced by most women. This pain occurs toward the end of the menstrual cycle in the week or so before you get your period. These problems have been resolved in the new breast pain chart. Danazol was the most effective drug, with bromocriptine and. Fibrocystic change of the breast is a nonspecific term, commonly understood as a continuum of physiologic. In the last decade, case-control studies have reported that cyclical mastalgia could be. 11 - other international versions of ICD-10 N60. Diagnosis, Breast pain. To make a full assessment of the cause, all patients require a full history, examination and, sometimes, investigations. Ibuprofen. 5 ± 6. [17,18] The Cardiff breast pain chart has been utilized and it is a daily chart for monitoring breast pain, as shown in Figure 1. In majority of women, mastalgia is a manifestation of “aberration in normal development and involution” (ANDI). Because of this cyclical relation, mastalgia is generally a condition of premenopausal women, The exactMajority of them presented with cyclical mastalgia (57. cyclic mastalgia ICD-10 code N64. 9%). In population surveys, more than 60% of women report that they have experienced cyclical mastalgia which they grade as severe. The sample in this study accounted for a prevalence of 16% of all the women who were seen. 05). , 4 there are difficulties in accepting the organic explanation as the entire explanation for the syndrome. Sangat jarang kasus mastalgia berhubungan dengan kanker. In one study, 200 international units (IU) of vitamin E taken twice daily for two months improved symptoms in women with cyclic breast pain. Severe mastalgia was the dominant feature in 10 women with diffuse fibrocystic disease of the breast as judged by palpation and mammography and verified histologically. 2 days of moderate-severe mastalgia monthly. 0 and 36. History will often reveal the temporal association of cyclical mastalgia with the menstrual cycle, but the best way to assess whether pain is cyclical is to ask the patient to complete a breast pain. Selain itu, penggunaan obat penghilang rasa nyeri seperti paracetamol dan ibuprofen juga bisa dapat membantu meringankan gejala. Flaxseed should be considered as a first-line treatment for cyclical mastalgia. References in the ICD-10-CM Index to Diseases and Injuries applicable to the clinical term "mastalgia". Pain aggravating upon any sort of sexual activity. 6%) reported menstrual delay. This is the American ICD-10-CM version of N60. Pourmoghadam N, et al. Cyclical mastalgia is the most common type of breast pain and is characterized by discomfort that is most prominent during the luteal phase of ovulation, improving. 1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 4) and treated with evening primrose. Asthma is a Mastalgia is considered the most common benign breast disorder in women during the fertile period by a prevalence rate of about 65% [1–3]. Mastalgia is the commonest breast symptom presenting to general practitioners and breast surgeons alike. Mastalgia is a common estrogenic adverse effect and can raise concerns regarding breast cancer. 1. 10. 5% with recurrent fibroadenoma, 13. Evaluation Treatment Key Points Mastalgia (breast pain) is common and can be localized or diffuse and unilateral or bilateral. Although it is one of the leading breast symptoms for which women seek medical attention, it is believed that mastalgia may be generally underreported and under-studied (). Gejala nyeri payudara siklik berupa: Terjadi sebelum atau selama. Background:Cyclic mastalgia is a common breast condition among women worldwide. Pre-menstrual syndrome (PMS) refers to a set of menstrually related, chronic, cyclical, physical and emotional symptoms occurring in the luteal. Cyclical mastalgia (CM) is the common symptoms in women, which is experienced many times in their life. Toremifen effectively relieves moderate and severe cyclicalmastalgia and tends to exert a positive therapeutic effect on noncyclical mastalgia and does not increase the incidence of intolerable adverse event. Tamoxifen 10 mg daily or danazol 200 mg daily should beWhat is mastalgia? Mastalgia is breast pain and is generally classified as either cyclical (associated with menstrual periods) or noncyclic. cyclical mastalgia individually for the three treatment groups compared with the placebo group (EPO, p=0. This type of breast pain is. 4 ICD-10 code description Cyclical breast pain can range intensity during menstruation Primary outcomes 1. 8% and all of the patients with breast cancer in this group was postmenopausal. 3% with a severe form. Objectives:To determine the prevalence and factors. 8%) were with non cyclic pain. 1016/S1072-7515(97)00095-1 Corpus ID: 27768991; Cyclical mastalgia: prevalence and impact in an outpatient breast clinic sample. 5%, respectively . 4 ICD-10 code description Mastodynia Primary outcomes 1 Description Intensity of mastalgia Timepoint before and after intervention Method of measurement Visual analogue scale (VAS) 2 Description Serum level of prolactin Timepoint before and after intervention Method of measurement Lab test Secondary. J Psychosom Obstet Gynaecol. Cyclic mastalgia is treated symptomatically with lifestyle modification, analgesics, and hormonal therapy. Among the mastalgia cases, among the various clinical risk factors, H/O Mastalgia was the most prevalent (38%) followed by the Cyclical mastalgia (33%). (I A) 9. 4. N61. 0 cm measured on a 10. Cyclical mastalgia: prevalence and associated health and behavioral factors. In the last decade, case-control studies have reported that cyclical mastalgia could be considered as an independent risk factor for breast cancer. 1997;185(5):466-70. Abstract: A randomized, double‐blind, placebo‐controlled, multicenter clinical trial was conducted with 111. DOI: 10. Cyclical breast main is specifically pain which arises with a direct correlation to the monthly menstrual cycle. The etiology of breast pain can be classified into three major categories: cyclic, noncyclical, and extra-mammary. 2021; 4 (1): p. The pain may come from the breast. N64. 42 years. Eleven women (34. Mastalgia. The breast is tender to touch. 59 became effective on October 1, 2023. 7A - other international versions of ICD-10 C84. 9%. Cyclic breast pain resolves. The 2024 edition of ICD-10-CM N64. 2. Heavy breasts. Usually starts during the luteal phase of the cycle (within 2 weeks before. 018). A primary concern for patients with mastalgia is that it is related to breast cancer. Infections of breastfeeding mothers like mastitis can also lead to swelling, warmth, and one-sided breast pain. Symptoms may worsen during certain parts of the menstrual cycle due to hormonal stimulation. 9±11. Scar tissue. In the non-cyclical mastalgia group, no patient had peak prolactin release greater than 4000 mU/l and none responded to therapy. (I A) 9. @article{Pruthi2010VitaminEA, title={Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. Breast cysts are a very common diagnosis among women and one of the most common reasons for a referral to a breast clinic. N61. 4 Mastodynia. Cyclic Mastalgia ICD-10 code N64. 39 patients with cyclic mastalgia were prospectively evaluated from July 2006 to August 2007 at Fatih University, Çankaya Hospital. (I A) 8. Danazol offers good pain control in mastalgia but with distressing side effects, where as Oil of Evening Primrose (OEP) also showed goodPain control but without much distressingSide effects. It often presents as diffuse bilateral pain but. The early onset mastalgia in this study requires further exploration for determination of its risk factors. Next Term: Masters Allen Syndrome. Endocrine status of cyclical mastalgia patients @article{Parlati1988HormonalPI, title={Hormonal profile in benign breast disease. The commonest cause is cyclical mastalgia. Noncyclic breast pain. 4 • Definitive Diagnosis o Non-cyclical Mastalgia – d/t pain that has progressed over the last few months. This type of breast pain lines up with your menstrual cycle. Tailoring treatment to type of breast pain. Introduction. Most women with this disorder (77. Most breast cancers do not cause pain. Granulomatous mastitis, left breast. Berikut beberapa gejalanya: Gejala mastalgia siklik: Perasaan payudara yang lebih berat dan nyeri. 3 ). Danazol is a very effective agent for severe breast pain and nodularity, with an overall improvement rate of 70%. The ABC of benign breast disease. Topical non-steroidal anti-inflammatory gel, such as diclofenac 2% in pluronic lethicin organogel, should be considered for pain control for localized treatment of mastalgia. 1016/0140-6736(90)90278-d. 27% of multipl e fibroadenoma, 12. Non. Other causes of mastalgia. Raised PRL levels haveMastalgia can be separated into four main groups, cyclical mastalgia, non-cyclical mastalgia, chest wall pain, and non-chest wall pain [] (Table 4. Ya, nyeri yang terasa pada payudara ini memang bisa terjadi pada siapa saja. The Mean age ± SD in women with cyclic mastalgia and control were (28. 2 The former is assumed to be due to. 9 may differ. Health Problems (ICD-10) include the condition under benign mammary dysplasia (category N60) and sub-. Poor sleep quality (PSQI > 5) was present in 59% (n = 69) of the women with NCBP and 38% (n = 17) of the controls (p = 0. 200 mg-800 mg q 6 h. 4 ICD-10 code description Cyclical breast pain can range intensity during menstruation Primary outcomes 1. The etiology of mastalgia is not understood clearly, but highly effective treatment with hormonal medications is suggestive of a hormonal basis, especially with respect to cyclic mastalgia. In our study, breast cancer rate in patients with mastalgia (n = 646) was 0. common than cyclical mastalgia and more common in women in their 40s. Browse for your desired term or condition, or search for a specific disease / condition. Danazol is an antigonadotropin and the only prescription-required drug approved by the U. Thus, we carry out this study to determine the efficacy of evening primrose oil (EPO) for mastalgia treatment in women. Cyclical mastalgia has been estimated by population-based surveys to affect from 22% to 41% of women [2, 4–6], with higher prevalence rates seen in breast clinics (30–69%) [7–10]. These patients were managed with various kind of medical agents. If the pain is associated with the menstrual cycle, the condition is referred to as cyclical mastalgia (cyclical breast pain). However, premenstrual breast tenderness is a. Background: Mastalgia or breast pain common benign breast disorder in women in her. Although largely ignored both scientifically and clinically in the United States, this condition merits further biopsychosocial investigation. Most women with this disorder (77. Introduction. Hal tersebut normal terjadi dan tidak berbahaya. Applicable To. The 2020 version of ICD-10-CM N62 becomes effective on October 1, 2019, replacing the previous edition. The Comparative Study of Therapeutic effect of Vitamin B6 or E on Cyclic Mastalgia Protocol summary Summary Cyclic mastalgia is a common condition in women seen in primary care practices. Some women's breasts are unusually tender and lumpy, with symptoms of pain and dull heaviness that vary with the menstrual cycle. Fibrocystic breast disease is the most common benign type of breast disease, diagnosed in millions of women worldwide. All women had (E2) and (P). Cyclical breast/chest pain is a normal part of the menstrual cycle and usually not a cause for concern. 7 Day Meal Plan & Recipe Guide. Mastalgia tidak selalu berbahaya. 11 may differ. Breast pain may be divided in two major categories: cyclic pain and noncyclic pain. This paper reviews the various non- pharmacological interventions for the management of the mastalgia and an update to the current management protocols. M83. referral is recommended if cyclical breast pain is affecting quality of life or sleep, and has been ongoing for more than 3 months if the pain is unresponsive to first-line treatment. Breast pain (also known as breast tenderness, mastodynia, mammalgia, and mastalgia from the Greek μαστός mastos, "breast" and ἄλγος algos, "pain") is a medical symptom. The specific calculated prevalence of noncyclical and cyclical mastalgia was 13% and 3%, respectively, noncyclical one being most prevalent. bursitis due to use, overuse and pressure ( M70. Last revised in August 2021. CAUSES OF MASTALGIA. 4103/1735-9066. Kanker payudara ditandai dengan gejala, seperti benjolan atau penebalan pada payudara, keluarnya. Methods: From April 2011 to August 2012 female patients over age 12 who presented to surgical outpatient department with cyclical or non-cyclical mastalgia were included in the study. two thirds of women with mastalgia have cyclical pain and the remaining third have pain which is non-cyclical. It is influenced by hormonal changes over the menstrual. 1). Localized breast pain is usually caused by a focal disorder that causes a mass , such as a breast cyst, or an infection (eg, mastitis , abscess). 1 Approximately 60–70% of women suffer from moderate to severe breast pain in their lifetime among which 10–20% of the cases suffer from severe breast pain 2 who may need. Only a small proportion of patients seek medical advice from their general practice team • breast pain can be cyclical and non-cyclical and is most common between the ages of 30 and 50 years. 27% of multipl e fibroadenoma, 12. life, Health Care for Women International, DOI: 10. Diet, medications,. It is possible that other foreign versions of ICD-10 N62. Key Words: Mastalgia, cyclic, non-cyclic, prevalence, reassurance. In our study. 8% to 2% (12). Young women (<or = 35 years) were more than three times as likely to have had a mammogram (75%) if they regularly experienced cyclical mastalgia than if they did not (24%; p<0. Side effects at this low dose for 3 months are minimal and include irregular periods and hot flashes. 001). If you have cyclical breast pain, your GP may reassure you that what you’re experiencing is a normal part of your monthly cycle. 2%) were with cyclic pain and 15(28. 10; and EPO plus vitamin E, p=0. ; This is the American ICD-10-CM version of. Fibrocystic breast disease is now called fibrocystic breast changes or fibrocystic breasts because the. Existing randomized controlled studies of tamoxifen showed efficacy in 71% to 96% of patients with cyclic breast. Berikut beberapa gejalanya: Gejala mastalgia siklik: Perasaan payudara yang lebih berat dan nyeri. Cyclical breast pain comes and goes regularly related to the menstrual cycle (monthly period). It affects up to two-thirds of women, with one in ten women having moderate-to-severe pain. 13, 14 Although pain is often mild, up to 11% of women experience severe pain, and. Severe breast pain or mastalgia is a common symptom, affecting up to 70% of the female population at some time in their lives. Most breast cancers do not cause pain. The two most common concerns of patients with mastalgia are fear of breast cancer and the presence of severe pain that affects the quality of life. The pain may be constant or it may occur only occasionally, and it can occur in men, women and transgender people. For claims with a date of service on or after October 1, 2015, use an equivalent ICD-10-CM code (or codes). Increased water retention in the breast and ductal ectasia has been suggested to be the principal causes of CM [ 4 ]. Semantic Scholar extracted view of "Tamoxifen therapy for cyclical mastalgia: dose. This is the American ICD-10-CM version of N64. Mastalgia is a symptom rather than a diagnosis, and presents in different ways depending on the type. Cancer (usually intraductal carcinoma or invasive ductal carcinoma) causes < 10% of cases. What is mastalgia? Mastalgia is breast pain. This is the American ICD-10-CM version of N61. And it is important to note, that more often than not, the breast pain is not associated with breast cancer. 2%) than those without mastalgia (9. 4 may differ. Meskipun ditandai dengan rasa nyeri pada payudara, tetapi mastalgia tidak berkaitan dengan kanker payudara. (II-3 B) 3. The berry of the chaste tree contains a number of active constituents: flavonoids (i. Sharp or burning pain. Prevalence and impact of cyclic mastalgia in a United States clinic-based sample. Summary. 59 may differ. doi: 10. If she has no pain on next day, she fills a. 6%) met criteria for PMS. A good history, examination and targeted imaging can help to delineate the underlying cause of mastalgia and therefore guide treatment options. When evaluating the intensity of the symptom, reassurance was effective in 85. By using CKS, you agree to the licence set out in the CKS End User Licence Agreement. TLDR. N64. Noncyclical mastalgia [4] Unilateral or bilateral breast pain, usually located over the costal cartilage. Irritation associated with soreness. Factors associated with Mastalgia: 1. The 2024 edition of ICD-10-CM N64. 4 ICD-10 code description Mastodynia Primary outcomes. Cyclical mastalgia is breast pain with premenstrual exacerbation occurring in a regular cyclic manner with every menstrual cycle []. Results from two-sample t-test showed a nonsignificant decrease in cyclical mastalgia individually for the three treatment groups compared with the placebo group (EPO, p=0. Benign breast disease is an umbrella term for various non-malignant lesions, such as tumors, trauma, mastalgia, and nipple. Mastodynia Billable Code. It is most commonly minor or moderate and is accepted as part of the normal changes of the. Usually occurs in one part of one breast. 2014 Sep 23;111(7):1269-74. The two most common concerns of patients presenting with mastalgia are: the fear of breast cancer and the. Studies have shown that those presenting with mastalgia are psychologically no different from women attending outpatients for other conditions. Berikut ini penjelasannya: 1. A study in Ireland showed (3): 3,331 reported mastalgia as the only symptom Penyebab mastalgia memang sulit dipastikan. Data menunjukkan 70 persen wanita pernah mengalami mastalgia setidaknya satu kali seumur hidupnya. Typically, it occurs in the second half of the monthly cycle, becoming worse in the days just before a period; orCyclical breast pain is related to the menstrual cycle. 11 is applicable to adult patients aged 15 -. Mastalgia and breast cysts run a chronic relapsing course throughout life with improvement at menopause. Introduction: Mastalgia or breast pain (syn: mastodynia) is a common breast symptom experienced by females of reproductive age; the reported prevalence ranges from 41% to 79% (1-4). 1 Department of Radiology, Division of Breast Imaging, Penn State Health, Milton S. This mastalgia can occur regularly for years until menopause, can interfere with usual activities, and is associated with elevated utilization of mammography among young women. There are 2 main types of mastalgia: Cyclical breast pain. Breast pain can range from mild to severe. The usual dose of Danazol for treatment of mastalgia is 100–400 mg per day. A study in Ireland showed (3): 3,331 reported mastalgia as the only symptomThe major signs/symptoms of HMG are as follows: cyclical/non-cyclical breast pain, nodular breast or nodular breast mass, with nipple discharge in some patients. Both surgery and radiation therapy for breast cancer can cause scar tissue formation. 7 ± 5. The compliance rate (subjects reporting that they were ei- ther “complying fully” or “complying to some degree”) was 52. There are a number of causes including infection and benign (non-cancerous) breast lumps. Representative examples of non-neoplastic disorders include fibrocystic disease, gynecomastia, and. 6%, respectively, while 47. Mastodynia (Painful breasts) In: diseases of the Breast, 2nd Edition JB. Jika pernah, itulah yang disebut sebagai mastalgia. In a randomized controlled trial of Centchroman vs. , 4 there are difficulties in accepting the organic explanation as the entire explanation for the syndrome. Breast pain is usually classed as either cyclical or non-cyclical: Cyclical breast pain - where the pain is related to the menstrual cycle. Top 5 most commonly. 1185/030079904125003377.